Current Context: Pennsylvania’s innovation economy is deeply regional. Pittsburgh anchors world leading expertise in AI, robotics, and advanced manufacturing while also building a burgeoning life sciences cluster connected to its health systems and research institutions. Philadelphia continues to expand its leadership in biotech, pharmaceuticals, and applied AI in life sciences, positioning the city as one of the nation’s fastest-growing health innovation hubs. State College and surrounding areas provide strength in materials science, agriculture, and energy research, while the northeast/Lehigh Valley, the northwest, anchored by Erie, and central Pennsylvania, bring resource-rich energy corridors and emerging tech manufacturing footprints.
Despite these assets, the commonwealth’s innovation economy remains uneven. Pennsylvania ranked 15th in the Milken Institute’s 2022 State Technology and Science Index, placing it in Tier 2 nationally. While the state performs strongly in research and risk capital inputs, it lags in technology talent density and tech sector concentration. By intentionally developing regional innovation corridors, Pennsylvania can connect these complementary strengths – energy, AI, robotics, and life sciences, while addressing gaps in talent and technology diffusion.
Potential Game Changer:
Create designated Regional AI Activation Corridors supported by “communities of practice” that integrate universities, health systems, advanced manufacturing, and energy development. By clustering and aligning investments across regions with a specific emphasis on AI adoption and R&D, these corridors can accelerate knowledge spillover, talent retention, and commercialization.
Key Metric: Net new jobs in AI, automation, and advanced technology occupations created within designated corridors, paired with median wage growth compared to statewide averages. Track corridor performance using Milken-aligned indicators:
- Tech Concentration and Dynamism (TCD): growth in high-tech and life sciences employment, startup formation, and regional business expansion.
- Technology and Science Workforce (TSW): increase in specialized STEM and health innovation occupations per capita within corridor regions.